Ajay Neginhal

This project automates DNA transformation and gene cloning protocols on the Opentrons OT-2 platform, improving throughput and reproducibility for routine lab workflows.

ResearchTBDAutomation Engineer

Automated DNA Transformation and Gene Cloning (Opentrons OT-2)

Automation workflows for DNA transformation and gene cloning on the Opentrons OT-2 platform.

Figure coming soon
Automated protocol workflow (placeholder).
Lab AutomationRoboticsBioengineeringPythonResearch

Key Reminders

  • Describe the end-to-end protocol automation and error handling.
  • Discuss calibration and volume accuracy considerations.
  • Highlight throughput and reproducibility gains.

Technologies

Opentrons OT-2PythonLiquid HandlingLab Automation

Problem and Scope

Automated DNA transformation and gene cloning protocols to improve reproducibility and reduce manual pipetting overhead.

System Architecture

Protocols were implemented as modular steps for reagent preparation, transformation, and incubation, with structured logging for traceability.

Figure coming soon
Automation workflow schematic placeholder.

python code

Code example forthcoming

Opentrons protocol step definition.

Hardware and Calibration

Calibration routines ensured accurate deck positioning and volume transfers across repeated runs.

Figure coming soon
Deck layout schematic placeholder.

Testing and Validation

Validation emphasized repeatability, contamination avoidance, and run-time reliability.

Figure coming soon
Validation metrics placeholder.

Demo and Next Steps

Future work includes expanded protocol libraries and integration with lab information systems.

Figure coming soon
Demo video placeholder.